Description

3-(3,5-Difluorophenyl)Oxetane is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the oxetane ring, which serves as a versatile and stable bioisostere, and the difluorophenyl moiety, which can dramatically influence a compound's physicochemical and metabolic properties. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who are engaged in the design and synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery programs, particularly for introducing metabolic stability and modulating lipophilicity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the difluorophenyl-oxetane scaffold can enhance biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique optical or surface properties.
• Ligand and Catalyst Development: Employed as a precursor for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Fluorine Chemistry Studies: A valuable substrate for investigating new fluorination reactions and the effects of fluorine atoms on molecular conformation.

Basic Information

Product Name	3-(3,5-Difluorophenyl)Oxetane
CAS No.	1395282-61-7
Molecular Formula	C9H8F2O
Molecular Weight	170.16 g/mol
Synonyms	3-(3,5-Difluorophenyl)oxetane; Oxetane, 3-(3,5-difluorophenyl)-; 3-(3,5-Difluorophenyl)oxacyclobutane; 1395282-61-7; 3,5-Difluorophenyloxetane
EINECS	Contact for details

Quality Control

Every batch of 3-(3,5-Difluorophenyl)Oxetane is produced and analyzed under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Typical: 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.