Description

1-(3,5-Difluorophenyl)Cyclobutanol is a high-purity fluorinated cyclobutanol derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique structural motif, which combines a substituted cyclobutyl ring with a difluorinated aromatic system, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas requiring fluorinated scaffolds.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and pesticides, where the difluorophenyl group can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent for creating specialty polymers and advanced materials with specific optical or electronic properties.
• Ligand Synthesis for Catalysis: Employed in the preparation of sophisticated chiral ligands and organocatalysts for asymmetric synthesis applications.
• Chemical Biology Probe Development: Utilized as a core structure for creating molecular probes and tags used in biochemical and diagnostic research.

Basic Information

Product Name	1-(3,5-Difluorophenyl)Cyclobutanol
CAS No.	1395282-03-7
Molecular Formula	C10H10F2O
Molecular Weight	184.18 g/mol
Synonyms	1-(3,5-Difluorophenyl)cyclobutan-1-ol; Cyclobutanol, 1-(3,5-difluorophenyl)-; 3,5-Difluoro-α-(1-hydroxycyclobutyl)benzene; 1-(3,5-Difluorophenyl)-1-cyclobutanol; 1395282-03-7; 1-(3,5-Difluorophenyl)cyclobutyl alcohol
EINECS	Contact for details

Quality Control

Our 1-(3,5-Difluorophenyl)Cyclobutanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and ISO standards ensures a reliable supply of this high-value intermediate for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.