Description

2-Borono-5-Bromobenzotrifluoride is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. Its unique structure, combining a boronic acid group with bromine and trifluoromethyl substituents, makes it a critical reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries to introduce key functional groups into target molecules efficiently.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and insecticides by incorporating the benzotrifluoride moiety, which often enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Production: Serves as a building block for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Polymer Chemistry: Employed to introduce functional aromatic units into specialty polymers, modifying their thermal, optical, or electronic properties.
• Chemical Research & Development: A versatile reagent in academic and industrial labs for exploring new synthetic pathways and creating compound libraries for screening.
• Fluorine Chemistry: Acts as a valuable source of a trifluoromethylated aryl ring in the development of new fluorinated materials and catalysts.

Basic Information

Product Name	2-Borono-5-Bromobenzotrifluoride
CAS No.	1394346-22-5
Molecular Formula	C7H4BBrF3O2
Molecular Weight	252.82 g/mol
Synonyms	5-Bromo-2-(trifluoromethyl)phenylboronic acid; (5-Bromo-2-(trifluoromethyl)phenyl)boronic acid; 2-Bromo-5-(trifluoromethyl)benzeneboronic acid; 2-Borono-5-bromobenzotrifluoride; Boronic acid, B-[5-bromo-2-(trifluoromethyl)phenyl]-; 1394346-22-5; 5-Bromo-α,α,α-trifluoro-o-tolylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Borono-5-Bromobenzotrifluoride is manufactured and tested under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to ensure the material meets your specific research or production requirements. Our quality commitment aligns with cGMP principles for advanced intermediates, supporting regulatory filings in target industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.