Description

5-Bromo-3-Fluoro-2-Iodoanisole is a high-purity, multi-halogenated anisole derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides by introducing halogenated aromatic motifs into lead compounds.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings due to the presence of bromo and iodo substituents.
• Chemical Biology: Employed as a probe or tag in bioconjugation and the development of molecular imaging agents.
• Organic Synthesis: A versatile reagent for introducing halogenated anisole units into more complex molecules for structure-activity relationship (SAR) studies.

Basic Information

Product Name	5-Bromo-3-Fluoro-2-Iodoanisole
CAS No.	1394291-47-4
Molecular Formula	C7H5BrFIO
Molecular Weight	345.92 g/mol
Synonyms	1-Bromo-5-fluoro-2-iodo-3-methoxybenzene; 2-Iodo-5-bromo-3-fluoroanisole; 3-Fluoro-5-bromo-2-iodoanisole; Benzene, 1-bromo-5-fluoro-2-iodo-3-methoxy-; Anisole, 5-bromo-3-fluoro-2-iodo-; 5-Bromo-3-fluoro-2-iodo-1-methoxybenzene
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Fluoro-2-Iodoanisole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.