Description

1-(3-Aminopyrrolidin-1-Yl)Ethanone Hydrochloride is a high-purity pharmaceutical intermediate and building block characterized by its pyrrolidine core functionalized with an amino and an acetyl group. This compound is of significant value in medicinal chemistry for the synthesis of novel drug candidates, particularly those targeting the central nervous system and other therapeutic areas. It is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the creation of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new drug discovery programs.
• Protease Inhibitor Development: Serves as a precursor in the creation of inhibitors for various enzymatic targets.
• Ligand Synthesis for Receptor Targeting: Employed in the preparation of ligands for neurological and GPCR targets.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific novel chemical entities.

Basic Information

Product Name	1-(3-Aminopyrrolidin-1-Yl)Ethanone Hydrochloride
CAS No.	1394041-16-7
Molecular Formula	C6H13N2O·HCl
Molecular Weight	164.64 (Free base) / 201.10 (HCl salt)
Synonyms	1-(3-Aminopyrrolidin-1-yl)ethanone hydrochloride; 1-(3-Amino-1-pyrrolidinyl)ethanone hydrochloride; 3-Amino-1-acetylpyrrolidine hydrochloride; N-(3-Aminopyrrolidin-1-yl)acetamide hydrochloride; 1-Acetyl-3-aminopyrrolidine hydrochloride; Ethanone, 1-(3-amino-1-pyrrolidinyl)-, hydrochloride; 1394041-16-7
EINECS	Contact for details

Quality Control

Our 1-(3-Aminopyrrolidin-1-Yl)Ethanone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.