Description

Cyclohexanecarboxylic Acid, 4,4-Difluoro-1-Hydroxy-, Ethyl Ester is a high-purity fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters for its unique structural features, combining a cyclohexane core with fluorine and ester functionalities, which are critical for modulating the physicochemical properties of target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly those requiring fluorinated motifs for enhanced metabolic stability, bioavailability, or receptor binding affinity.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the introduction of fluorine atoms can improve biological activity and environmental persistence profiles.
• Liquid Crystal & OLED Material Research: Acts as a precursor or modifying agent in the synthesis of fluorinated organic compounds for electronic applications, contributing to desired dielectric and optical properties.
• Advanced Polymer Chemistry: Employed as a monomer or cross-linking agent to incorporate fluorinated cyclohexyl units into specialty polymers, potentially enhancing chemical resistance and thermal stability.
• Chemical Biology & Probe Development: Useful for synthesizing fluorinated probes and tags used in imaging, diagnostics, and studying biological mechanisms.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Detail
Product Name	Cyclohexanecarboxylic Acid, 4,4-Difluoro-1-Hydroxy-, Ethyl Ester
CAS No.	1393824-30-0
Molecular Formula	C9H14F2O3
Molecular Weight	208.20 g/mol
Synonyms	4,4-Difluoro-1-hydroxycyclohexanecarboxylic acid ethyl ester; Ethyl 4,4-difluoro-1-hydroxycyclohexanecarboxylate; 1-Hydroxy-4,4-difluorocyclohexanecarboxylic Acid Ethyl Ester; 4,4-Difluoro-1-hydroxy-cyclohexanecarboxylic acid ethyl ester; 1393824-30-0; UNII-9F6U4V8F4T
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 4,4-Difluoro-1-Hydroxy-, Ethyl Ester is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided and available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider an inert atmosphere to preserve optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.