Description

5-Bromo-4-Chloro-2-Nitrobenzonitrile is a high-purity, multi-functional aromatic nitrile building block used in advanced organic synthesis. This compound is valued for its unique halogenated nitrobenzonitrile structure, which provides multiple reactive sites for constructing complex molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as medicinal chemistry, ligand synthesis, and the development of functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Synthesis: Serves as a versatile building block for developing novel herbicides, fungicides, and insecticides due to its halogen and nitro functional groups.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials where its aromatic core and substituents influence material properties.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of chemical probes, activity-based probes, and bioconjugation reagents.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing complex azo dyes and high-performance pigments.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse biaryl structures.

Basic Information

Product Name	5-Bromo-4-Chloro-2-Nitrobenzonitrile
CAS No.	1393442-14-2
Molecular Formula	C7H2BrClN2O2
Molecular Weight	261.46 g/mol
Synonyms	4-Chloro-5-bromo-2-nitrobenzonitrile; 2-Nitro-4-chloro-5-bromobenzonitrile; Benzonitrile, 5-bromo-4-chloro-2-nitro-; 5-Bromo-4-chloro-2-nitro-benzonitrile
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Chloro-2-Nitrobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and scale-up. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.