Description

1H-Imidazole-2-Carbonitrile Hydrochloride is a high-value, heterocyclic building block and key synthetic intermediate in advanced organic chemistry. This compound matters for its crucial role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. Pharmaceutical researchers, agrochemical developers, and specialty chemical manufacturers need this precise intermediate for its ability to introduce the imidazole-carbonitrile pharmacophore, which is pivotal in creating compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new fungicides, herbicides, and plant growth regulators that leverage the imidazole core for biological activity.
• Material Science: Serves as a precursor for functionalized polymers, ligands for catalysis, and organic electronic materials.
• Chemical Synthesis: Employed in heterocyclic chemistry as a versatile reagent for constructing complex, nitrogen-containing ring systems via further functionalization.
• Bioconjugation & Probe Development: Useful in creating labeled compounds and biochemical probes for diagnostic and research applications.

Basic Information

Product Name	1H-Imidazole-2-Carbonitrile Hydrochloride
CAS No.	1392803-62-1
Molecular Formula	C4H4N3·HCl
Molecular Weight	129.56 g/mol
Synonyms	2-Cyanoimidazole Hydrochloride; Imidazole-2-carbonitrile Hydrochloride; 1H-Imidazole-2-carbonitrile, hydrochloride; 2-Cyano-1H-imidazole hydrochloride; 2-Imidazolecarbonitrile hydrochloride; 1H-Imidazole-2-carbonitrile HCl; 2-CN-Imidazole·HCl
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-2-Carbonitrile Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with customer requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.