Description

4-Cyanopiperidine-1-Sulfonyl Chloride is a versatile and high-value sulfonyl chloride derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in its dual functionality, enabling the efficient introduction of both the piperidine scaffold and a reactive sulfonyl chloride group into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of small molecule drugs, especially protease inhibitors and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring sulfonamide or sulfonate functionalities.
• Chemical Biology & Proteomics: Acts as a reactive handle for activity-based protein profiling (ABPP) and the development of covalent enzyme inhibitors.
• Material Science Research: Employed in the creation of functional polymers and advanced materials with specific surface properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses producing specialized intermediates for client R&D programs.

Basic Information

Product Name	4-Cyanopiperidine-1-Sulfonyl Chloride
CAS No.	1392803-35-8
Molecular Formula	C7H9ClN2O2S
Molecular Weight	220.68 g/mol
Synonyms	1-Piperidinesulfonyl chloride, 4-cyano-; 4-Cyano-1-piperidinesulfonyl chloride; 4-Cyanopiperidine-1-sulfonyl chloride; Piperidine-1-sulfonyl chloride, 4-cyano-; 4-Cyanopiperidine sulfonyl chloride; 1-(Chlorosulfonyl)-4-cyanopiperidine; 4-CN-Pip-SO2Cl
EINECS	Contact for details

Quality Control

Our 4-Cyanopiperidine-1-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.