Description

Phenol, 2-Fluoro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, multi-functional boronic ester derivative of phenol, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for constructing complex molecules. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, facilitating the development of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorinated compounds and complex biaryl structures.
• Agrochemical Synthesis: Used to construct novel herbicide and pesticide molecules, leveraging the stability and reactivity of the boronic ester group.
• Material Science & OLED Development: Building block for creating advanced organic electronic materials, including charge-transport layers and emissive materials in OLED displays.
• Ligand & Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and tags for imaging and diagnostic applications.
• Polymer & Resin Modification: Enables the functionalization of polymer backbones to introduce specific phenolic and fluorinated properties.

Basic Information

Product Name	Phenol, 2-Fluoro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	1392234-97-7
Molecular Formula	C12H16BFO3
Molecular Weight	238.07 g/mol
Synonyms	2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; (3-Fluoro-4-hydroxyphenyl)boronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-fluorophenol; 2-Fluoro-5-(pinacolatoboryl)phenol; 3-Fluoro-4-hydroxybenzeneboronic acid pinacol ester; PINACOL 2-FLUORO-5-PHENYLBORONATE; 2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol
EINECS	Contact for details

Quality Control

Our production of Phenol, 2-Fluoro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analysis including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.