Description

Asenapine 11-Hydroxysulfate-13Cd3 is a stable isotope-labeled analog of a key metabolite of the antipsychotic drug asenapine. This compound is essential for conducting precise and reliable quantitative bioanalytical studies, particularly in pharmacokinetics and drug metabolism research. It serves as a critical internal standard for scientists and researchers in pharmaceutical development and clinical laboratories, ensuring accurate measurement of asenapine and its metabolites in complex biological matrices.

Application

• Primary use as an Internal Standard in Liquid Chromatography-Mass Spectrometry (LC-MS/MS) bioanalysis for asenapine studies.
• Quantification of asenapine and its metabolites in pharmacokinetic (PK) and toxicokinetic (TK) profiling.
• Metabolite identification and structural elucidation in drug metabolism and disposition (DMPK) research.
• Supporting clinical trial analysis for therapeutic drug monitoring and compliance.
• Method development and validation in regulatory bioanalysis to meet FDA, EMA, and ICH guidelines.
• Use in forensic toxicology for the accurate detection of asenapine.

Basic Information

Product Name	Asenapine 11-Hydroxysulfate-13Cd3
CAS No.	1391745-00-8
Molecular Formula	C₁₇H₁₅D₃ClNO₄S *
Molecular Weight	Contact for details
Synonyms	11-Hydroxyasenapine Sulfate-13Cd3
Asenapine 11-O-Sulfate-d3 (13C-labeled)
Asenapine N-Oxide Sulfate Metabolite-d3
5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole-11-ol sulfate-d3 (13C-labeled)
Org 5220 Metabolite Sulfate-d3
SYCRIT Metabolite Standard-d3
13C-labeled Asenapine Hydroxysulfate
EINECS	Contact for details

* Formula representation is illustrative. Contact us for the exact, detailed molecular formula.

Quality Control

Every batch of Asenapine 11-Hydroxysulfate-13Cd3 is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, supported by comprehensive analytical data including NMR, MS, and HPLC. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, isotopic enrichment, and solvent content to meet the stringent requirements of analytical reference standard applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This material is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.