Description

Carbocisteine-13C3 is a stable isotope-labeled analog of the mucolytic agent carbocisteine, where three carbon atoms are replaced with the carbon-13 isotope. This compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring the highest accuracy and reliability in analytical measurements. It is primarily required by pharmaceutical research and development laboratories, clinical research organizations, and analytical testing facilities engaged in pharmacokinetic studies, drug metabolism research, and bioanalytical method development.

Application

• Internal Standard for LC-MS/MS quantification of Carbocisteine in biological matrices (plasma, serum, urine).
• Metabolite tracking and pathway elucidation in drug metabolism and pharmacokinetics (DMPK) studies.
• Bioanalytical method development and validation for regulatory submissions (FDA, EMA).
• Quality control and assurance in pharmaceutical manufacturing of carbocisteine-based formulations.
• Clinical research for accurate therapeutic drug monitoring (TDM).
• Use in stable isotope dilution assays (SIDA) for precise quantification in complex samples.

Basic Information

Product Name	Carbocisteine-13C3
CAS No.	1391068-19-1
Molecular Formula	C513C3H9NO4S
Molecular Weight	182.17 g/mol (labeled)
Synonyms	S-Carboxymethyl-L-cysteine-13C3; (R)-2-Amino-3-[(carboxy-13C)methylthio]propanoic acid-13C2; L-Carbocisteine-13C3; Mucodyne-13C3 (labeled); Carbocisteine (13C3); S-Carboxymethylcysteine-13C3; 13C3-Carbocisteine; Isotopically Labeled Carbocisteine
EINECS	Contact for details

Quality Control

Our Carbocisteine-13C3 is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically ≥99 atom % 13C), chemical purity (by HPLC), and confirmation of structure. We adhere to cGMP principles for the production of reference standards, ensuring traceability, consistency, and reliability for your critical research and regulatory work.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere. Keep container tightly sealed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Isotopic Purity	≥99 atom % 13C
Chemical Purity (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.