Description

o-Desethyl-o-Propyl Methisosildenafil is a high-purity pharmaceutical intermediate and research chemical. This compound is of significant interest for its role in the synthesis and development of active pharmaceutical ingredients (APIs) within the PDE-5 inhibitor class. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in advanced synthesis and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel PDE-5 inhibitor compounds for therapeutic research.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control in API manufacturing.
• Biochemical Research: Employed in pharmacological studies to investigate enzyme inhibition mechanisms and structure-activity relationships (SAR).
• Process Chemistry Development: Serves as a critical intermediate for optimizing scalable and efficient synthetic routes in pilot plants.
• Custom Synthesis: A starting material for the preparation of specialized analogs and derivatives for proprietary drug discovery programs.

Basic Information

Item	Details
Product Name	o-Desethyl-o-Propyl Methisosildenafil
CAS No.	1391053-82-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Methisosildenafil Impurity; o-Desethyl o-Propyl Methisosildenafil; Desethyl Propyl Methisosildenafil; PDE-5 Inhibitor Intermediate; 1391053-82-9; 2-[2-Ethoxy-5-(4-ethylpiperazin-1-yl)sulfonylphenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one derivative
EINECS	Contact for details

Quality Control

Our o-Desethyl-o-Propyl Methisosildenafil is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) documenting full specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.