Description

3-Des[2-(Dimethylamino)Ethyl]-3-[1-Methyl-1-(Methylamino)Ethyl] Almotriptan is a key pharmaceutical intermediate and reference standard in the synthesis of advanced therapeutic agents. This compound is critical for research and development in the pharmaceutical industry, offering a high-purity building block for creating novel drug candidates. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and analytical laboratories focused on neurology and migraine treatment research.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of triptan-class drugs and their novel derivatives.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical analysis.
• Active Pharmaceutical Ingredient (API) Research: Serves as a precursor or a structural analog in the R&D of new neurological and cardiovascular APIs.
• Process Chemistry: Employed in route scouting and optimization studies for the scalable manufacturing of complex organic molecules.
• Metabolite Studies: Used in pharmacokinetic and drug metabolism research to understand the biotransformation pathways of related therapeutics.

Basic Information

Product Name	3-Des[2-(Dimethylamino)Ethyl]-3-[1-Methyl-1-(Methylamino)Ethyl] Almotriptan
CAS No.	1391053-74-9
Molecular Formula	C18H29N3O2S
Molecular Weight	351.51 g/mol
Synonyms	Almotriptan Impurity; Almotriptan Related Compound; 3-Des-DMAE-3-MMAE Almotriptan; 1-[[3-[1-Methyl-1-(Methylamino)ethyl]pyrrolidin-5-yl]methyl]sulfonylmethylpyrrole; Almotriptan Derivative; Almotriptan Metabolite Analog; AXERT Impurity
EINECS	Contact for details

Quality Control

Our 3-Des[2-(Dimethylamino)Ethyl]-3-[1-Methyl-1-(Methylamino)Ethyl] Almotriptan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.