Description

n-Demethylricinine-13C3 is a stable isotope-labeled analog of the alkaloid ricinine, specifically labeled with three carbon-13 atoms. This compound is of critical importance for use as an internal standard in quantitative mass spectrometry, ensuring high accuracy and precision in analytical measurements. It is primarily needed by research institutions, pharmaceutical companies, and contract research organizations (CROs) engaged in metabolomics, pharmacokinetic studies, and forensic toxicology where precise quantification of ricinine or related metabolites is required.

Application

• Mass Spectrometry Internal Standard: Essential for accurate quantification of ricinine in complex biological matrices (e.g., plasma, urine, tissue) using LC-MS/MS or GC-MS.
• Metabolomics Research: Used as a labeled tracer to study the metabolic pathways and biotransformation of ricinine and related compounds.
• Forensic Toxicology: Critical for the definitive identification and precise measurement of ricinine exposure in forensic casework.
• Pharmaceutical R&D: Supports drug metabolism and pharmacokinetics (DMPK) studies for compounds with ricinine-like structures.
• Method Development & Validation: Serves as a reference material for developing and validating robust, regulatory-compliant analytical methods.
• Quality Control in Reference Material Production: Used to certify the purity and concentration of unlabeled ricinine reference standards.

Basic Information

Product Name	n-Demethylricinine-13C3
CAS No.	1391053-00-1
Molecular Formula	C713C3H8N2O2
Molecular Weight	170.14 g/mol (approx.)
Synonyms	3-Cyano-4-methoxy-2-oxo-1,2-dihydropyridine-13C3; Ricinine-13C3 (demethylated); 1,2-Dihydro-4-methoxy-2-oxo-3-pyridinecarbonitrile-13C3; 4-Methoxy-2-oxo-1,2-dihydro-3-pyridinecarbonitrile-13C3; [13C3]-n-Demethylricinine; Isotopically Labeled Ricinine Derivative
EINECS	Contact for details

Quality Control

Our n-Demethylricinine-13C3 is manufactured under strict quality control protocols to ensure the highest isotopic and chemical purity for sensitive analytical applications. Each batch is fully characterized by NMR, HPLC, and mass spectrometry to confirm identity, purity, and isotopic enrichment. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Isotopic Purity (by MS)	≥ 99% 13C3
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.