Description

5-Amino-N'-[2,3-Bis(Acetyloxy)Propyl]-n-(2,3-Dihydroxypropy)-2,4,6-Triiodo-n-Methyl-1,3-Benzenedicarboxamide is a high-purity, triiodinated organic compound designed for advanced pharmaceutical synthesis. This specialized intermediate is critical for the development of next-generation non-ionic, low-osmolar X-ray contrast media agents. It is primarily required by research institutions and fine chemical manufacturers engaged in the production of diagnostic imaging pharmaceuticals, where precise molecular structure and purity are paramount for safety and efficacy.

Application

• Key Intermediate for X-ray Contrast Media: Serves as a crucial building block in the synthesis of modern, non-ionic iodinated contrast agents used in computed tomography (CT) scans, angiography, and urography.
• Pharmaceutical Research & Development: Utilized in the discovery and process development of new diagnostic imaging compounds with improved safety profiles and pharmacokinetics.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, iodine-containing molecules with specific solubility and biodistribution properties.
• Radiology Agent Precursor: Acts as a precursor molecule that can be further functionalized to tailor the hydrophilicity, viscosity, and osmolality of the final contrast agent formulation.

Basic Information

Product Name	5-Amino-N'-[2,3-Bis(Acetyloxy)Propyl]-n-(2,3-Dihydroxypropy)-2,4,6-Triiodo-n-Methyl-1,3-Benzenedicarboxamide
CAS No.	1391051-75-4
Molecular Formula	C21H27I3N3O8
Molecular Weight	839.17 g/mol
Synonyms	5-Amino-N'-[2,3-bis(acetyloxy)propyl]-N-(2,3-dihydroxypropyl)-2,4,6-triiodo-N-methylisophthalamide; Iomeprol Intermediate; Triiodinated Benzene Dicarboxamide Derivative; Non-ionic Contrast Agent Intermediate; CAS 1391051-75-4; 1,3-Benzenedicarboxamide, 5-amino-N'-[2,3-bis(acetyloxy)propyl]-N-(2,3-dihydroxypropyl)-2,4,6-triiodo-N-methyl-
EINECS	Contact for details

Quality Control

Our 5-Amino-N'-[2,3-Bis(Acetyloxy)Propyl]-n-(2,3-Dihydroxypropy)-2,4,6-Triiodo-n-Methyl-1,3-Benzenedicarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 10 ppm
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.