Description

n-(2-Fluoro-5-Nitrophenyl)-3,5-Bis(Trifluoromethyl)Benzamide is a high-value, multi-fluorinated aromatic amide building block designed for advanced chemical synthesis. This compound matters because its unique structure, featuring both nitro and trifluoromethyl groups, provides critical electronic and steric properties for developing novel active molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery programs.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the fluorine atoms.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers and advanced organic materials.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a molecular probe in biochemical assays.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects requiring complex fluorinated aromatic systems.

Basic Information

Product Name	n-(2-Fluoro-5-Nitrophenyl)-3,5-Bis(Trifluoromethyl)Benzamide
CAS No.	1389521-16-7
Molecular Formula	C15H7F7N2O3
Molecular Weight	420.22 g/mol
Synonyms	2-Fluoro-5-nitro-N-[3,5-bis(trifluoromethyl)phenyl]benzamide; 3,5-Bis(trifluoromethyl)-N-(2-fluoro-5-nitrophenyl)benzamide; Benzamide, N-(2-fluoro-5-nitrophenyl)-3,5-bis(trifluoromethyl)-; 1389521-16-7; AKOS025247315; FT-0696126; NS00023826; BRN 27736273
EINECS	Contact for details

Quality Control

Our n-(2-Fluoro-5-Nitrophenyl)-3,5-Bis(Trifluoromethyl)Benzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.