Description

n-((2R)-2-Amino-3-Hydroxypropyl)(tert-Butoxy)Carboxamide is a high-purity chiral building block and protected amino alcohol derivative. This compound is critical for the synthesis of complex molecules where stereochemical integrity and functional group protection are paramount. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of novel therapeutic agents.
• Peptide Chemistry: Used in the preparation of modified amino acids and as a building block for peptide backbone engineering.
• Protecting Group Strategy: The tert-butoxycarboxamide (Boc) group provides a stable, orthogonal protecting group for amines in complex synthetic routes.
• Asymmetric Synthesis: Employed as a precursor or auxiliary in catalytic asymmetric reactions to induce chirality.
• Bioconjugation: Facilitates the creation of linker molecules for antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Research: Used in the synthesis of probes and inhibitors for studying biological pathways and enzyme function.

Basic Information

Product Name	n-((2R)-2-Amino-3-Hydroxypropyl)(tert-Butoxy)Carboxamide
CAS No.	1389385-19-6
Molecular Formula	C8H18N2O3
Molecular Weight	190.24 g/mol
Synonyms	(2R)-2-Amino-3-hydroxypropyl tert-butylcarbamate; (R)-2-Amino-3-hydroxypropyl carbamic acid tert-butyl ester; (R)-3-Hydroxy-1-((tert-butoxycarbonyl)amino)propan-2-aminium; Boc-D-serinol; tert-Butyl N-[(2R)-2-amino-3-hydroxypropyl]carbamate; (R)-2-((tert-Butoxycarbonyl)amino)-3-hydroxypropylamine; 1389385-19-6
EINECS	Contact for details

Quality Control

Our n-((2R)-2-Amino-3-Hydroxypropyl)(tert-Butoxy)Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.