Description

2-(2-Fluoro-4-(Methylsulfonyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a versatile intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex fluorinated and sulfonylated biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific fluorinated aromatic structures.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Medicinal Chemistry: Employed in the discovery and optimization of new chemical entities through high-throughput screening and library synthesis.
• Catalyst & Ligand Development: Useful in the preparation of novel ligands and catalysts for transition metal-catalyzed reactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Item	Details
Product Name	2-(2-Fluoro-4-(Methylsulfonyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1384951-71-6
Molecular Formula	C13H18BFO4S
Molecular Weight	300.16 g/mol
Synonyms	4,4,5,5-Tetramethyl-2-[2-fluoro-4-(methylsulfonyl)phenyl]-1,3,2-dioxaborolane; 2-Fluoro-4-(methylsulfonyl)phenylboronic acid pinacol ester; (2-Fluoro-4-(methylsulfonyl)phenyl)boronic acid pinacol ester; 1384951-71-6; 2-Fluoro-4-methanesulfonylphenylboronic acid pinacol ester; Pinacol (2-fluoro-4-(methylsulfonyl)phenyl)boronate
EINECS	Contact for details

Quality Control

Our 2-(2-Fluoro-4-(Methylsulfonyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.