Description

3-Cyano-4-Fluoro-5-Methoxyphenylboronic Acid Pinacol Ester is a high-purity, multi-functional boronic ester building block essential for modern synthetic chemistry. Its value lies in its stability and reactivity, making it a superior alternative to the corresponding boronic acid for demanding cross-coupling reactions. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-couplings for synthesizing active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific fluorinated and methoxylated aromatic structures.
• Material Science Research: Serves as a precursor for creating advanced organic electronic materials, such as OLEDs and organic semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of novel bidentate ligands and organometallic catalysts.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up manufacturing under cGMP conditions.

Basic Information

Product Name	3-Cyano-4-Fluoro-5-Methoxyphenylboronic Acid Pinacol Ester
CAS No.	1383985-45-2
Molecular Formula	C14H17BFNO3
Molecular Weight	277.10 g/mol
Synonyms	2-(3-Cyano-4-fluoro-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (3-Cyano-4-fluoro-5-methoxyphenyl)boronic acid pinacol ester; 4-Fluoro-5-methoxy-3-cyanophenylboronic acid pinacol ester; 3-Cyano-4-fluoro-5-methoxybenzeneboronic acid pinacol ester; Boronic acid, B-(3-cyano-4-fluoro-5-methoxyphenyl)-, 1,1-dimethylethyl ester; 1383985-45-2; 3-CN-4-F-5-MeO-PhBpin
EINECS	Contact for details

Quality Control

Our 3-Cyano-4-Fluoro-5-Methoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with full analytical data are provided to guarantee compliance with your project specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.