Description

5-Fluoro-2-Methoxyphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound matters as a key Suzuki-Miyaura cross-coupling reagent, enabling the efficient and selective construction of complex biaryl structures critical in advanced material and pharmaceutical development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing fluorinated biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the specific substitution pattern imparts desirable biological activity and stability.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and OFETs, where fluorinated aromatic units can tune electronic properties and molecular packing.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in catalysis, including those for asymmetric synthesis and polymerization processes.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Fluoro-2-Methoxyphenylboronic Acid Pinacol Ester
CAS No.	1383806-53-8
Molecular Formula	C₁₃H₁₈BFO₃
Molecular Weight	252.09 g/mol
Synonyms	5-Fluoro-2-methoxyphenylboronic acid pinacol ester; (5-Fluoro-2-methoxyphenyl)boronic acid pinacol ester; 2-Methoxy-5-fluorophenylboronic acid pinacol ester; 5-Fluoro-2-methoxybenzeneboronic acid pinacol ester; Pinacol (5-fluoro-2-methoxyphenyl)boronate; B-(5-Fluoro-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 1383806-53-8
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Methoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with lot-specific data are provided to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of research and cGMP-oriented production environments.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized; ensure containers are properly sealed after each use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.