Description

n-Ethyl L-Z-Valinamide is a specialized chiral building block and protected amino acid derivative. This compound is of significant value in advanced pharmaceutical synthesis, particularly for the development of peptide-based therapeutics and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for constructing complex molecular architectures with high stereochemical purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel peptide drugs and protease inhibitors.
• Peptide Chemistry: Serves as a protected valine derivative for solid-phase and solution-phase peptide synthesis (SPPS).
• API Development: Used in research and process development for new Active Pharmaceutical Ingredients requiring specific valinamide motifs.
• Bioconjugation: Potential utility in linker chemistry for antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Research: Employed as a tool compound in studying enzyme-substrate interactions and metabolic pathways.
• Fine Chemical Synthesis: A building block for synthesizing complex organic molecules with defined stereocenters in agrochemical and material science research.

Basic Information

Product Name	n-Ethyl L-Z-Valinamide
CAS No.	1381929-59-4
Molecular Formula	C10H20N2O2
Molecular Weight	200.28 g/mol
Synonyms	L-Valinamide, N-ethyl-; (S)-2-((Ethylamino)carbonyl)amino)-3-methylbutanoic acid; Z-L-Val-NHEt; Nα-Carbobenzoxy-L-valine ethylamide; CBZ-L-Valine ethylamide; N-Ethyl-N'-[(benzyloxy)carbonyl]-L-valinamide; Benzyl (1-((ethylamino)oxomethyl)-2-methylpropyl)carbamate
EINECS	Contact for details

Quality Control

Our n-Ethyl L-Z-Valinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.