Description

9,10-Didehydro Cabergoline is a high-purity pharmaceutical intermediate and reference standard, structurally related to the potent dopamine agonist cabergoline. This compound is critical for research and development in the pharmaceutical sector, particularly for studying metabolic pathways and synthesizing novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, analytical testing facilities, and manufacturers of active pharmaceutical ingredients (APIs) for neurological and endocrine applications.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis and structural analysis of cabergoline analogs and related dopaminergic compounds.
• Reference Standard: Used as a certified reference material (CRM) in analytical methods development and validation for quality control testing.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research to understand the biotransformation of cabergoline.
• Process Chemistry: Acts as a building block in the scale-up and optimization of API manufacturing processes for neurological therapies.
• Academic Research: Utilized in university and institutional labs for biochemical and pharmacological studies targeting dopamine receptors.

Basic Information

Product Name	9,10-Didehydro Cabergoline
CAS No.	1380085-95-9
Molecular Formula	C26H37N5O2
Molecular Weight	451.61 g/mol
Synonyms	9,10-Didehydrocabergoline; Cabergoline Impurity; Cabergoline Related Compound; (6aR,9R,10aR)-7-[(2R)-2-[(Methylamino)ethyl]-4-(2,3-dihydro-1H-inden-2-yl)-1-piperazinyl]-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide; 1-[(6-Allylergolin-8β-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea (dehydro derivative); FCE-21336 Impurity
EINECS	Contact for details

Quality Control

Our 9,10-Didehydro Cabergoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR, MS), and residual solvent analysis to ensure it meets stringent specifications for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with the agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.