Description

Boc-(S)-1-(4-Bromophenyl)-2-Hydroxyethylamine is a high-purity, chiral building block featuring a Boc-protected amine and a benzylic hydroxyl group. This compound is critical for the synthesis of complex, optically active molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing peptidomimetics and active pharmaceutical ingredient (API) intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Peptidomimetic Scaffold: Used to introduce the (S)-1-(4-bromophenyl)-2-hydroxyethyl moiety into peptide backbones to modulate bioavailability and receptor binding affinity.
• Asymmetric Synthesis: Serves as a versatile starting material or chiral auxiliary in catalytic asymmetric transformations.
• Agrochemical Research: Employed in the development of novel, enantiomerically pure herbicides and fungicides.
• Ligand and Catalyst Development: Useful for constructing chiral ligands for metal-catalyzed reactions.
• Chemical Biology Probes: Incorporated into molecular probes for studying enzyme mechanisms and protein-protein interactions.

Basic Information

Product Name	Boc-(S)-1-(4-Bromophenyl)-2-Hydroxyethylamine
CAS No.	1379546-68-5
Molecular Formula	C₁₃H₁₈BrNO₃
Molecular Weight	316.19 g/mol
Synonyms	(S)-tert-Butyl (1-(4-bromophenyl)-2-hydroxyethyl)carbamate; (S)-N-Boc-2-Amino-2-(4-bromophenyl)ethanol; N-(tert-Butoxycarbonyl)-L-4-bromophenylethanolamine; Boc-L-4-BrPhe-ol; (S)-1-(4-Bromophenyl)-2-((tert-butoxycarbonyl)amino)ethanol; tert-Butyl ((1S)-1-(4-bromophenyl)-2-hydroxyethyl)carbamate; (S)-2-((tert-Butoxycarbonyl)amino)-2-(4-bromophenyl)ethan-1-ol
EINECS	Contact for details

Quality Control

Our Boc-(S)-1-(4-Bromophenyl)-2-Hydroxyethylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.