Description

5-(Chloromethyl)-2-Fluorobenzenesulfonamide is a high-purity, multi-functional chemical building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both a reactive chloromethyl group and a fluorinated benzenesulfonamide core, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the sulfonamide and fluorine motifs.
• Material Science Research: Serves as a precursor for functionalized polymers or specialty chemicals with tailored surface properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Ligand and Catalyst Development: Acts as a starting material for creating novel ligands and organocatalysts used in asymmetric synthesis.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	5-(Chloromethyl)-2-Fluorobenzenesulfonamide
CAS No.	1379371-14-8
Molecular Formula	C7H7ClFNO2S
Molecular Weight	223.65 g/mol
Synonyms	2-Fluoro-5-(chloromethyl)benzenesulfonamide; Benzenesulfonamide, 5-(chloromethyl)-2-fluoro-; 5-(Chloromethyl)-2-fluorobenzene-1-sulfonamide; 2-Fluoro-5-chloromethylbenzenesulfonamide; 1-(Chloromethyl)-4-fluoro-3-sulfamoylbenzene; 4-Fluoro-3-sulfamoylbenzyl chloride
EINECS	Contact for details

Quality Control

Every batch of 5-(Chloromethyl)-2-Fluorobenzenesulfonamide is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for research-grade and intermediate chemicals. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and meet your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.