Description

5-Bromo-2-Methoxy-4-Methylbenzonitrile is a high-purity, multi-functional benzonitrile derivative and a valuable synthetic intermediate. Its molecular structure, featuring bromine and methoxy substituents, makes it a critical building block for constructing complex organic molecules in advanced research and development. This compound is essential for pharmaceutical chemists, agrochemical researchers, and material scientists engaged in the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Serves as a core building block for developing novel herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and advanced polymers due to its electron-withdrawing nitrile group and aromatic core.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for creating molecular probes, enzyme inhibitors, and labeled compounds for biological studies.
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of specialized dyes and pigments, contributing to color fastness and specific spectral properties.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.

Basic Information

Product Name	5-Bromo-2-Methoxy-4-Methylbenzonitrile
CAS No.	1379313-90-2
Molecular Formula	C9H8BrNO
Molecular Weight	226.07 g/mol
Synonyms	4-Methyl-5-bromo-2-methoxybenzonitrile; 2-Methoxy-4-methyl-5-bromobenzonitrile; 5-Bromo-2-methoxy-p-tolunitrile; Benzonitrile, 5-bromo-2-methoxy-4-methyl-; 1379313-90-2; 5-Br-2-MeO-4-Me-Bn
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Methoxy-4-Methylbenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.