Description

5-(Pyrrolidine-1-Carbonyl)-1H-Indazole is a high-purity, advanced pharmaceutical intermediate featuring a unique indazole core functionalized with a pyrrolidine carbonyl moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for creating novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of potential drug candidates targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Serves as a starting material for synthesizing probes and inhibitors used to study specific biological pathways and enzyme functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of novel chemical entities for clinical trials.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and bioorganic chemistry.

Basic Information

Product Name	5-(Pyrrolidine-1-Carbonyl)-1H-Indazole
CAS No.	1379264-55-7
Molecular Formula	C₁₂H₁₃N₃O
Molecular Weight	215.25 g/mol
Synonyms	1H-Indazole-5-carboxylic acid, 1-pyrrolidinyl ester; 5-(1-Pyrrolidinecarbonyl)-1H-indazole; 5-(Pyrrolidine-1-carbonyl)-1H-indazole; Pyrrolidine-1-carboxylic acid (1H-indazol-5-yl) ester; 1379264-55-7; 5-(Pyrrolidin-1-ylcarbonyl)-1H-indazole
EINECS	Contact for details

Quality Control

Our 5-(Pyrrolidine-1-Carbonyl)-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.