Description

5-(Trifluoromethyl)Thiazole-2-Carbaldehyde is a high-value fluorinated heterocyclic building block, distinguished by its reactive aldehyde group and electron-withdrawing trifluoromethyl substituent. This combination makes it a critical intermediate for synthesizing complex molecules with enhanced metabolic stability and lipophilicity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by advanced material scientists.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, antiviral agents, and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysts for organic transformations.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for designing molecular probes and tags due to its reactive aldehyde functionality for bioconjugation.

Basic Information

Product Name	5-(Trifluoromethyl)Thiazole-2-Carbaldehyde
CAS No.	1379174-19-2
Molecular Formula	C5H2F3NOS
Molecular Weight	181.14 g/mol
Synonyms	2-Formyl-5-(trifluoromethyl)thiazole; 5-(Trifluoromethyl)-2-thiazolecarboxaldehyde; 5-(Trifluoromethyl)-1,3-thiazole-2-carbaldehyde; 2-Thiazolecarboxaldehyde, 5-(trifluoromethyl)-; 1379174-19-2; 5-Trifluoromethylthiazole-2-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 5-(Trifluoromethyl)Thiazole-2-Carbaldehyde is manufactured and tested under strict quality management systems. We ensure compliance with relevant industry standards for fine chemical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.