Description

2,4-Difluoro-5-Methylbenzamide is a high-purity fluorinated benzamide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This intermediate is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorine and amide functionalities into their target compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the difluoro-methylbenzamide structure contributes to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers and liquid crystals, where fluorine atoms can modify material properties like thermal stability and solubility.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production under cGMP or ISO standards for client-specific molecules.

Basic Information

Product Name	2,4-Difluoro-5-Methylbenzamide
CAS No.	1379078-33-7
Molecular Formula	C8H7F2NO
Molecular Weight	171.15 g/mol
Synonyms	5-Methyl-2,4-difluorobenzamide; 2,4-Difluoro-5-methyl-benzamide; Benzamide, 2,4-difluoro-5-methyl-; 1379078-33-7; AI3-63500; AKOS040759176; ZINC000068049806; SCHEMBL21824079
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-5-Methylbenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.