Description

5-Methoxy-4-Methylnicotinonitrile is a high-purity, versatile pyridine derivative and a key chemical intermediate. Its unique substitution pattern makes it a valuable synthon for constructing complex heterocyclic systems in advanced pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working in drug discovery and fine chemical synthesis. The product is supplied under strict quality control to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as electron-transport layers and light-emitting components.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and fluorescent tags to study biological processes.
• Custom Synthesis and Contract Manufacturing: A starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Methoxy-4-Methylnicotinonitrile
CAS No.	1379034-62-4
Molecular Formula	C8H8N2O
Molecular Weight	148.16 g/mol
Synonyms	4-Methyl-5-methoxynicotinonitrile; 5-Methoxy-4-methyl-3-pyridinecarbonitrile; 3-Cyano-5-methoxy-4-methylpyridine; 3-Pyridinecarbonitrile, 5-methoxy-4-methyl-; Nicotinonitrile, 5-methoxy-4-methyl-
EINECS	Contact for details

Quality Control

Every batch of 5-Methoxy-4-Methylnicotinonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and mass spectrometry is supplied with each shipment. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.