Description

(3,3-Difluorocyclohexyl)Methanamine Hydrochloride CAS NO 1379025-24-7 is a high-purity, fluorinated organic building block supplied as a stable hydrochloride salt. This compound is valued for its unique cyclohexylamine scaffold bearing geminal difluoride groups, which are critical for modulating the physicochemical and metabolic properties of target molecules. It is primarily utilized by pharmaceutical and agrochemical research organizations as a key intermediate in the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A versatile building block for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, metabolic diseases, and anti-infectives.
• Agrochemical Synthesis: Serves as a precursor in the creation of advanced pesticides and herbicides, where the difluorocyclohexyl moiety can enhance biological activity and environmental stability.
• Chemical Biology Probe Development: Used in the design and synthesis of molecular probes for studying enzyme function and biological pathways, leveraging its fluorine atoms for potential 19F NMR applications.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialty polymers and advanced materials with tailored surface properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	(3,3-Difluorocyclohexyl)Methanamine Hydrochloride
CAS No.	1379025-24-7
Molecular Formula	C7H14ClF2N
Molecular Weight	185.64 g/mol
Synonyms	(3,3-Difluorocyclohexyl)methanamine HCl; 1-(3,3-Difluorocyclohexyl)methanamine hydrochloride; (3,3-Difluorocyclohexyl)methylamine hydrochloride; Cyclohexanemethanamine, 3,3-difluoro-, hydrochloride; 1379025-24-7; (3,3-Difluorocyclohexyl)methanamine monohydrochloride
EINECS	Contact for details

Quality Control

Our (3,3-Difluorocyclohexyl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, which includes data from NMR (1H, 13C, 19F), HPLC, and residual solvent analysis. Our quality commitment supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.