Description

n-(3,5-Difluorophenyl)-2,2,2-Trifluoroacetamide is a high-purity fluorinated acetamide derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique trifluoroacetyl and difluorophenyl groups, which are instrumental in modulating the biological activity and physicochemical properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for incorporating fluorine atoms to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Material Science Research: Serves as a precursor for specialty polymers and advanced materials requiring specific fluorinated aromatic components.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	n-(3,5-Difluorophenyl)-2,2,2-Trifluoroacetamide
CAS No.	1378573-08-0
Molecular Formula	C8H4F5NO
Molecular Weight	225.12 g/mol
Synonyms	2,2,2-Trifluoro-N-(3,5-difluorophenyl)acetamide; 3,5-Difluorophenyltrifluoroacetamide; N-(3,5-Difluorophenyl)trifluoroacetamide; 2,2,2-Trifluoroacet-3',5'-difluoroanilide; Acetamide, N-(3,5-difluorophenyl)-2,2,2-trifluoro-; 1378573-08-0; TFA-3,5-difluoroanilide
EINECS	Contact for details

Quality Control

Our n-(3,5-Difluorophenyl)-2,2,2-Trifluoroacetamide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent quality suitable for sensitive R&D and scale-up applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.