Description

Velpatasvir-A12 is a high-purity pharmaceutical intermediate and reference standard, identified by CAS NO 1377604-63-1. This compound is critical for research, development, and quality control processes in the synthesis of modern antiviral therapeutics. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and analytical laboratories engaged in the production and validation of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of Velpatasvir and related antiviral compounds.
• Reference Standard: Used for method development, validation, and quality control (QC) testing in analytical laboratories.
• Research & Development: Serves as a crucial material for preclinical studies and process chemistry optimization.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the final stages of API production under controlled GMP environments.
• Regulatory Submissions: Provides essential characterization data for drug master files (DMFs) and regulatory filings (e.g., FDA, EMA).

Basic Information

Product Name	Velpatasvir-A12
CAS No.	1377604-63-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Velpatasvir Impurity A12; Velpatasvir Related Compound A12; Methyl N-[(2S)-1-[(2S,5S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-azido-5-(2,7-diazaspiro[3.5]nonan-7-yl)-6-oxohexyl]pyrrolidin-2-yl]carbamate; Velpatasvir Intermediate A12; A12 Intermediate; GS-5816 Impurity A12
EINECS	Contact for details

Quality Control

Our Velpatasvir-A12 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific pharmacopeial or internal specifications for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.