Description

2-Cyano-5-Fluorophenylboronic Acid is a high-purity, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique molecular structure, featuring both a cyano and a fluoro substituent, makes it an exceptionally versatile reagent for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science sectors for advanced R&D and production.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Liquid Crystal & OLED Material Production: Serves as a building block for electron-transport materials and other functional components in display and lighting technologies.
• Polymer & Resin Modification: Incorporated into specialty polymers to impart specific chemical resistance, thermal stability, or optical properties.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and sensors for diagnostic and research applications.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	2-Cyano-5-Fluorophenylboronic Acid
CAS No.	1375109-01-5
Molecular Formula	C7H5BFNO2
Molecular Weight	164.93 g/mol
Synonyms	(2-Cyano-5-fluorophenyl)boronic Acid; 5-Fluoro-2-cyanophenylboronic Acid; 2-Fluoro-5-cyanophenylboronic Acid; Boronic acid, B-(2-cyano-5-fluorophenyl)-; 1375109-01-5; 2-Cyano-5-fluorobenzeneboronic acid
EINECS	Contact for details

Quality Control

Our 2-Cyano-5-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.