Description

4-(2-n-Boc-Aminoethyl)-4-Pipecoline is a specialized Boc-protected piperidine derivative, serving as a crucial chiral building block in advanced organic synthesis. This high-purity intermediate is essential for constructing complex molecular architectures with precise stereochemistry. It is primarily utilized by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, particularly in medicinal chemistry for creating potential drug candidates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug discovery.
• Agrochemical Synthesis: Building block for developing novel, stereochemically-defined pesticides and herbicides.
• Asymmetric Catalysis: Used as a precursor or ligand component in chiral catalyst systems for enantioselective transformations.
• Peptidomimetic Research: Integral for constructing constrained peptide analogs and protease inhibitors due to its pipecolic acid scaffold.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity chiral intermediates.

Basic Information

Product Name	4-(2-n-Boc-Aminoethyl)-4-Pipecoline
CAS No.	1374654-40-6
Molecular Formula	C13H26N2O2
Molecular Weight	242.36 g/mol
Synonyms	1-Boc-4-(2-aminoethyl)-4-piperidinecarboxylic acid methyl ester; tert-Butyl 4-(2-aminoethyl)-4-piperidinecarboxylate; 4-(2-((tert-Butoxycarbonyl)amino)ethyl)piperidine-4-carboxylic acid; 4-Pipecoline, 4-(2-((1,1-dimethylethoxy)carbonyl)amino)ethyl]-; 1-(tert-Butoxycarbonyl)-4-(2-aminoethyl)piperidine-4-carboxylic acid; Boc-4-(2-Aminoethyl)-4-piperidinecarboxylic Acid; 1374654-40-6
EINECS	Contact for details

Quality Control

Our 4-(2-n-Boc-Aminoethyl)-4-Pipecoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) guidelines where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.