Description

5-Bromo-2-Mercapto-Benzonitrile is a versatile and high-value aromatic nitrile derivative containing both bromine and thiol functional groups. This compound is a critical synthetic intermediate prized for its dual reactivity, enabling the construction of complex heterocyclic and pharmaceutical scaffolds. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for applications in drug discovery, ligand synthesis, and polymer modification.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing benzothiophene or related sulfur heterocycles.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science: Intermediate in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research: A valuable reagent for organic synthesis, enabling C-S and C-C bond-forming reactions via its reactive thiol and cyano groups.

Basic Information

Product Name	5-Bromo-2-Mercapto-Benzonitrile
CAS No.	1374518-00-9
Molecular Formula	C7H4BrNS
Molecular Weight	214.08 g/mol
Synonyms	2-Cyano-4-bromobenzenethiol; 4-Bromo-2-mercaptobenzonitrile; 5-Bromo-2-sulfanylbenzonitrile; 2-Mercapto-5-bromobenzonitrile; Benzonitrile, 5-bromo-2-mercapto-; 5-Bromo-2-thiocyanatobenzene (tautomer); 2-Bromo-5-cyanobenzenethiol
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Mercapto-Benzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle under an inert atmosphere for long-term storage of bulk quantities. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.