Description

2-(4-Fluoro-Phenyl)-Cyclopropanecarboxylic Acid Amide is a high-purity, fluorinated cyclopropane derivative serving as a critical synthetic intermediate. Its value lies in the unique structural combination of the cyclopropane ring and the fluorinated aromatic system, which is pivotal for modulating the biological activity and physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries engaged in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and metabolic conditions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom and rigid cyclopropane structure can enhance efficacy and environmental stability.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and protein-ligand interactions in biochemical research.
• Material Science Precursor: Potential intermediate for synthesizing specialty polymers or liquid crystals, leveraging its aromatic and alicyclic components.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and scaled-up processes.

Basic Information

Product Name	2-(4-Fluoro-Phenyl)-Cyclopropanecarboxylic Acid Amide
CAS No.	1374509-48-4
Molecular Formula	C10H10FNO
Molecular Weight	179.19 g/mol
Synonyms	2-(4-Fluorophenyl)cyclopropanecarboxamide; 2-(p-Fluorophenyl)cyclopropanecarboxamide; 4-Fluoro-α-(aminocarbonyl)cyclopropanebenzene; 1-(4-Fluorophenyl)cyclopropanecarboxamide (related isomer); F-CPPA; 2-(4-Fluorophenyl)cyclopropane-1-carboxamide; 1374509-48-4; 2-(4-Fluoro-phenyl)-cyclopropanecarboxylic acid amide
EINECS	Contact for details

Quality Control

Our 2-(4-Fluoro-Phenyl)-Cyclopropanecarboxylic Acid Amide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) documenting all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.