Description

4-Ethyl-3-Fluorophenylboronic Acid CAS NO 1374302-04-1 is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require a reliable, high-quality reagent for drug discovery, process development, and material science applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing a fluorinated biphenyl or biaryl scaffold.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that benefit from the unique properties of the fluorinated ethylphenyl group.
• Material Science Research: Serves as a monomer or precursor in the development of organic electronic materials, including polymers for OLEDs and organic semiconductors.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysts used in asymmetric synthesis and other specialized reactions.
• Chemical Biology & Probe Synthesis: Utilized to create molecular probes and labelled compounds for diagnostic and biochemical research applications.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses and CROs/CMOs serving the life sciences industry.

Basic Information

Product Name	4-Ethyl-3-Fluorophenylboronic Acid
CAS No.	1374302-04-1
Molecular Formula	C8H10BFO2
Molecular Weight	167.98 g/mol
Synonyms	(4-Ethyl-3-fluorophenyl)boronic acid; 3-Fluoro-4-ethylbenzeneboronic acid; B-(4-Ethyl-3-fluorophenyl)boronic acid; 4-Ethyl-3-fluorobenzeneboronic acid; (3-Fluoro-4-ethylphenyl)boronic acid; 4-Ethyl-3-fluorophenyl-B(OH)2; 1374302-04-1 (CAS)
EINECS	Contact for details

Quality Control

Our 4-Ethyl-3-Fluorophenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.