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Potassium 2,6-Dimethoxy-3-Pyridinetrifluoroborate CAS NO 1374247-42-3


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CAS No.:1374247-42-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Potassium 2,6-Dimethoxy-3-Pyridinetrifluoroborate is a high-purity organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its primary value lies in its enhanced stability and reactivity compared to traditional boronic acids, enabling more robust and efficient cross-coupling reactions. This advanced reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional molecules.

Application

  • Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl scaffolds, central to many drug discovery programs.
  • Pharmaceutical Intermediate Synthesis: Used in the production of complex active pharmaceutical ingredients (APIs) and candidate molecules.
  • Agrochemical Development: Employed in creating novel herbicides, fungicides, and insecticides with specific activity profiles.
  • Material Science Research: Serves as a precursor for organic electronic materials, such as those used in OLEDs and semiconductors.
  • Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands and organometallic catalysts.
  • Chemical Biology Probes: Facilitates the labeling and modification of biomolecules for diagnostic and research applications.

Basic Information

Product Name Potassium 2,6-Dimethoxy-3-Pyridinetrifluoroborate
CAS No. 1374247-42-3
Molecular Formula C7H8BF3KNO2
Molecular Weight 245.05 g/mol
Synonyms Potassium (2,6-Dimethoxypyridin-3-yl)trifluoroborate; 2,6-Dimethoxy-3-pyridinyltrifluoroborate Potassium Salt; 3-Pyridinyltrifluoroborate, 2,6-dimethoxy-, potassium salt; Potassium 2,6-Dimethoxy-3-pyridyltrifluoroborate; 2,6-Dimethoxy-3-pyridyltrifluoroboronic acid potassium salt
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Quality Control

Our Potassium 2,6-Dimethoxy-3-Pyridinetrifluoroborate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (1H, 11B, 19F), HPLC for purity, and KF titration for moisture content, to ensure it meets the high standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect reactivity. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
11B NMR Purity ≥ 95.0%
Water Content (KF) ≤ 2.0%
Solubility Soluble in polar aprotic solvents (e.g., DMF, DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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