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(S)-3,3'-Bis(3,5-Dichlorophenyl)-1,1'-Binapthyl-2,2'-Diyl Hydrogenphosphate CAS NO 1374030-20-2


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CAS No.:1374030-20-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(S)-3,3'-Bis(3,5-Dichlorophenyl)-1,1'-Binapthyl-2,2'-Diyl Hydrogenphosphate is a sophisticated chiral organophosphorus compound that serves as a highly effective catalyst and ligand in asymmetric synthesis. Its value lies in enabling the production of enantiomerically pure intermediates critical for advanced pharmaceuticals and agrochemicals. This product is essential for R&D chemists and process development scientists in the fine chemical, pharmaceutical, and specialty materials industries who require precise stereochemical control.

Application

  • Asymmetric Catalysis: Acts as a privileged chiral ligand for transition metal-catalyzed reactions, including hydrogenation, cross-coupling, and C-H activation.
  • Pharmaceutical Intermediate Synthesis: Key for constructing chiral centers in the development of active pharmaceutical ingredients (APIs) with high enantiomeric excess (ee).
  • Agrochemical Research: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
  • Material Science: Potential application in the development of chiral polymers and liquid crystals for advanced optical materials.
  • Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and process optimization.

Basic Information

Product Name (S)-3,3'-Bis(3,5-Dichlorophenyl)-1,1'-Binapthyl-2,2'-Diyl Hydrogenphosphate
CAS No. 1374030-20-2
Molecular Formula C44H24Cl4O4P2
Molecular Weight 828.42 g/mol
Synonyms (S)-3,3'-Bis(3,5-dichlorophenyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; (S)-BINOL-Derived Phosphoric Acid; (S)-3,3'-Bis(3,5-dichlorophenyl)-BINOL Phosphoric Acid; (S)-TRIP Analogue; Chiral Brønsted Acid Catalyst; (S)-BINOL-Phosphate Derivative; (S)-Axially Chiral Phosphoric Acid; (S)-3,3'-Diaryl-BINOL Phosphoric Acid
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Quality Control

Our production of (S)-3,3'-Bis(3,5-Dichlorophenyl)-1,1'-Binapthyl-2,2'-Diyl Hydrogenphosphate adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized by advanced analytical techniques, including chiral HPLC, to confirm identity and enantiomeric excess. Certificates of Analysis (COA) detailing purity, assay, and chiral purity are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; the container should be kept in a desiccator under an inert atmosphere for long-term stability.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Chiral Purity (HPLC) ≥ 99.0% ee
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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