Description

4-Fluoro-3-Methyl-5-(Trifluoromethyl)Cinnamic Acid, 97% is a high-purity fluorinated cinnamic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique combination of fluorine and trifluoromethyl groups, which are essential for modulating the physicochemical properties of target molecules, such as metabolic stability, lipophilicity, and bioavailability. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Material Science: Serves as a monomer or precursor for specialty polymers and liquid crystals with tailored optical and electronic properties.
• Chemical Synthesis: Acts as a versatile synthon for constructing complex organic frameworks via reactions like Heck coupling or Michael addition.
• Fluorine Chemistry Studies: Employed in academic and industrial R&D to study the effects of polyfluorination on molecular structure and reactivity.

Basic Information

Item	Detail
Product Name	4-Fluoro-3-Methyl-5-(Trifluoromethyl)Cinnamic Acid, 97%
CAS No.	1373921-81-3
Molecular Formula	C₁₁H₈F₄O₂
Molecular Weight	248.18 g/mol
Synonyms	4-Fluoro-3-methyl-5-(trifluoromethyl)cinnamic acid; (E)-3-[4-Fluoro-3-methyl-5-(trifluoromethyl)phenyl]acrylic acid; 3-(4-Fluoro-3-methyl-5-(trifluoromethyl)phenyl)-2-propenoic acid; 4-Fluoro-3-methyl-5-trifluoromethylcinnamic acid; 1373921-81-3; FC-03M5T-CA; Trifluoromethylfluorocinnamic acid derivative
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Methyl-5-(Trifluoromethyl)Cinnamic Acid, 97% is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure it meets the specified 97% minimum purity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency, supporting your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.