Description

4-Butoxy-2,6-Difluorophenylacetonitrile is a specialized fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries requiring high-purity, structurally complex intermediates for research and production will find this chemical essential for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas requiring fluorinated scaffolds.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the difluorophenyl moiety can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated aromatic components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Employed in the synthesis of specialty polymers and resins where the introduction of fluorine atoms can modify thermal stability, chemical resistance, and surface properties.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new reactions, catalytic processes, and the creation of complex molecular architectures.

Basic Information

Product Name	4-Butoxy-2,6-Difluorophenylacetonitrile
CAS No.	1373921-02-8
Molecular Formula	C₁₂H₁₃F₂NO
Molecular Weight	225.24 g/mol
Synonyms	2-(4-Butoxy-2,6-difluorophenyl)acetonitrile; (4-Butoxy-2,6-difluorophenyl)acetonitrile; 4-Butoxy-2,6-difluorobenzeneacetonitrile; 2,6-Difluoro-4-butoxyphenylacetonitrile; α-Cyano-4-butoxy-2,6-difluorotoluene; DFBP-Acetonitrile Intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4-Butoxy-2,6-Difluorophenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.