Description

2-Fluoro-5-Methoxy-3-(Trifluoromethyl)Phenylacetic Acid, 97% is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in its unique trifluoromethyl and methoxy-substituted phenylacetic acid structure, which is critical for modulating the physicochemical properties of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor in the design and production of novel herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance bioactivity and environmental stability.
• Liquid Crystal Materials: Used in the research and manufacturing of advanced liquid crystal displays (LCDs) due to its polarizable aromatic core and fluorine atoms, which influence dielectric anisotropy.
• Organic Electronic Materials: Acts as a building block for electron-transport materials or non-fullerene acceptors in organic photovoltaics (OPVs) and organic light-emitting diodes (OLEDs).
• Chemical Research & Development: Employed in academic and industrial labs for method development, catalysis studies, and exploring novel fluorination reactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules at various scales.

Basic Information

Product Name	2-Fluoro-5-Methoxy-3-(Trifluoromethyl)Phenylacetic Acid, 97%
CAS No.	1373920-85-4
Molecular Formula	C10H8F4O3
Molecular Weight	252.16 g/mol
Synonyms	[2-Fluoro-5-methoxy-3-(trifluoromethyl)phenyl]acetic acid; 2-(2-Fluoro-5-methoxy-3-(trifluoromethyl)phenyl)acetic acid; α-(2-Fluoro-5-methoxy-3-trifluoromethylphenyl)acetic acid; 2-Fluoro-5-methoxy-3-trifluoromethylbenzeneacetic acid; 1373920-85-4; 2-Fluoro-5-methoxy-3-(trifluoromethyl)benzenacetic acid; (2-Fluoro-5-methoxy-3-(trifluoromethyl)phenyl)acetic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methoxy-3-(Trifluoromethyl)Phenylacetic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the specified 97% minimum assay. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.