Description

2-Fluoro-5-Methoxy-3-(Trifluoromethyl)Phenylacetonitrile, 97% is a high-purity fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular scaffold, which combines fluorine atoms and a reactive cyano group, making it a versatile precursor for constructing complex molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl and fluorine groups enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals, organic semiconductors, and polymers with specific electronic or optical properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the fine chemical industry.

Basic Information

Product Name	2-Fluoro-5-Methoxy-3-(Trifluoromethyl)Phenylacetonitrile, 97%
CAS No.	1373920-64-9
Molecular Formula	C10H7F4NO
Molecular Weight	233.16 g/mol
Synonyms	2-Fluoro-5-methoxy-3-(trifluoromethyl)benzyl cyanide; [2-Fluoro-5-methoxy-3-(trifluoromethyl)phenyl]acetonitrile; 2-(2-Fluoro-5-methoxy-3-(trifluoromethyl)phenyl)acetonitrile; α-(2-Fluoro-5-methoxy-3-(trifluoromethyl)phenyl)acetonitrile; (2-Fluoro-5-methoxy-3-trifluoromethylphenyl)acetonitrile
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methoxy-3-(Trifluoromethyl)Phenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.