Description

1-Ethynyl-2-Fluoro-4-Methoxybenzene is a specialized fluorinated aromatic building block featuring both an ethynyl and a methoxy functional group. This unique molecular architecture makes it a valuable intermediate for constructing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for applications in medicinal chemistry, particularly in the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for constructing complex aromatic cores.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic systems.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research exploring the effects of fluorine substitution on molecular properties.
• Fine Chemical Synthesis: Used in custom and contract synthesis for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	1-Ethynyl-2-Fluoro-4-Methoxybenzene
CAS No.	1373500-30-1
Molecular Formula	C9H7FO
Molecular Weight	150.15 g/mol
Synonyms	2-Fluoro-4-methoxyphenylacetylene; 4-Methoxy-2-fluorophenylacetylene; 1-Ethynyl-2-fluoro-4-methoxybenzene; 2-Fluoro-4-methoxybenzeneacetylene; 2-Fluoro-4-methoxyphenylethyne; (2-Fluoro-4-methoxyphenyl)ethyne
EINECS	Contact for details

Quality Control

Our 1-Ethynyl-2-Fluoro-4-Methoxybenzene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality systems support development under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.