Description

(2S,3S)-2-Benzyl-3-(tert-Butyl)-4-(2,6-Dimethoxyphenyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphole is a high-purity, chiral organophosphorus compound with significant utility in advanced synthetic chemistry. Its primary value lies in its role as a sophisticated ligand or catalyst precursor in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. This product is essential for R&D and process chemistry teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel, optically active molecules.

Application

• Asymmetric Catalysis: Serving as a key chiral ligand or precursor for transition metal catalysts in enantioselective C-C and C-X bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: Enabling the stereocontrolled synthesis of complex, biologically active molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel, chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Methodology Development: A valuable tool for academic and industrial researchers exploring new catalytic systems and synthetic methodologies.
• Fine Chemical Production: Facilitating the manufacture of high-value, enantiomerically enriched flavors, fragrances, and electronic chemicals.

Basic Information

Product Name	(2S,3S)-2-Benzyl-3-(tert-Butyl)-4-(2,6-Dimethoxyphenyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphole
CAS No.	1373432-13-3
Molecular Formula	C27H31O3P
Molecular Weight	434.51 g/mol
Synonyms	2,3-Dihydrobenzo[d][1,3]oxaphosphole, 2-benzyl-3-(1,1-dimethylethyl)-4-(2,6-dimethoxyphenyl)-, (2S,3S)-; (2S,3S)-2-Benzyl-3-tert-butyl-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole; Chiral Dihydrobenzooxaphosphole Ligand; BDBO Ligand; (S,S)-Benzyl-tert-Butyl-Dihydrobenzooxaphosphole
EINECS	Contact for details

Quality Control

Our production of (2S,3S)-2-Benzyl-3-(tert-Butyl)-4-(2,6-Dimethoxyphenyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphole adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is fully characterized and undergoes rigorous analytical testing, including chiral HPLC and NMR, to confirm identity, enantiomeric excess, and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, well-ventilated area. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.