Description

3-(4-Amino-2-Fluoro-Phenyl)-Propionic Acid Methyl Ester is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its bifunctional reactivity, featuring both a protected carboxylic acid group and a primary aromatic amine, making it a versatile intermediate for constructing complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorescent Dye and Sensor Chemistry: Employed in the synthesis of advanced fluorophores and molecular sensors due to its amine and ester functional groups.
• Peptidomimetic and Bio-conjugation: The ester can be hydrolyzed to the acid or the amine can be functionalized, making it useful for creating peptide analogs and linker molecules.
• Material Science Research: Acts as a monomer or functionalizing agent in the production of specialty polymers with unique optical or electronic properties.

Basic Information

Product Name	3-(4-Amino-2-Fluoro-Phenyl)-Propionic Acid Methyl Ester
CAS No.	1373223-14-3
Molecular Formula	C10H12FNO2
Molecular Weight	197.21 g/mol
Synonyms	Methyl 3-(4-amino-2-fluorophenyl)propanoate; 2-Fluoro-4-(2-methoxycarbonylethyl)aniline; 3-(4-Amino-2-fluorophenyl)propanoic acid methyl ester; Methyl β-(4-amino-2-fluorophenyl)propionate; 4-Amino-2-fluorobenzene propanoic acid methyl ester; 1373223-14-3; Methyl 3-(4-amino-2-fluorophenyl)propionate
EINECS	Contact for details

Quality Control

Our 3-(4-Amino-2-Fluoro-Phenyl)-Propionic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.