Description

4,4,4-Trifluoro-2-Methyl-2-(2,2,2-Trifluoroethyl)Butan-1-Ol (Wx640374) is a high-value fluorinated alcohol building block, distinguished by its unique trifluoroethyl and trifluoromethyl substituents. This compound is critical for introducing fluorine atoms into target molecules, a key strategy for modulating their lipophilicity, metabolic stability, and binding affinity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology, CNS, and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in creating advanced fluorinated pesticides and herbicides, where fluorine enhances biological activity and environmental persistence.
• Advanced Material Precursor: Serves as a building block for specialty polymers, liquid crystals, and coatings requiring specific surface energy and chemical resistance properties.
• Organic Synthesis & Catalysis: Employed in asymmetric synthesis and as a ligand or co-catalyst in transition metal-catalyzed reactions due to its steric and electronic profile.
• Fluorine Chemistry Research: An essential reagent for academic and industrial research exploring new C-F bond formation methodologies and fluorine-specific reactivity.

Basic Information

Product Name	4,4,4-Trifluoro-2-Methyl-2-(2,2,2-Trifluoroethyl)Butan-1-Ol (Wx640374)
CAS No.	1372865-02-5
Molecular Formula	C7H8F6O
Molecular Weight	222.13 g/mol
Synonyms	2-Methyl-2-(2,2,2-trifluoroethyl)-4,4,4-trifluorobutan-1-ol; 4,4,4-Trifluoro-2-methyl-2-(2,2,2-trifluoroethyl)-1-butanol; 1-Butanol, 4,4,4-trifluoro-2-methyl-2-(2,2,2-trifluoroethyl)-; WX-640374; Wx640374
EINECS	Contact for details

Quality Control

Every batch of 4,4,4-Trifluoro-2-Methyl-2-(2,2,2-Trifluoroethyl)Butan-1-Ol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting your regulatory and process development needs. Certificates of Analysis (COA) detailing purity (typically by GC or HPLC), identity confirmation (IR, NMR), and impurity profiles are available for all commercial quantities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use and stored away from heat and ignition sources. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.