Description

(R)-n-(3-Nitrophenyl) tert-Butanesulfinamide CAS NO 1372133-77-1 is a high-purity chiral sulfinamide building block of significant importance in asymmetric synthesis. Its primary value lies in its role as a versatile chiral auxiliary and ligand for the stereoselective construction of complex nitrogen-containing molecules. This compound is essential for researchers and process chemists in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Asymmetric Synthesis: As a chiral auxiliary for the stereocontrolled synthesis of amines and amino acid derivatives.
• Pharmaceutical Intermediates: Key building block in the research and development of novel drug candidates, especially those targeting neurological and cardiovascular diseases.
• Catalyst and Ligand Preparation: Used in the synthesis of chiral catalysts and ligands for transition metal-catalyzed reactions.
• Agrochemical Research: Intermediate for the development of enantiomerically pure pesticides and herbicides.
• Academic & R&D: A critical reagent for methodological studies in organic and medicinal chemistry laboratories.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs offering bespoke chiral compound synthesis.

Basic Information

Product Name	(R)-n-(3-Nitrophenyl) tert-Butanesulfinamide
CAS No.	1372133-77-1
Molecular Formula	C₁₀H₁₄N₂O₃S
Molecular Weight	242.29 g/mol
Synonyms	(R)-N-(3-Nitrophenyl)-2-methylpropane-2-sulfinamide; (R)-tert-Butanesulfinamide, N-(3-nitrophenyl)-; (R)-2-Methyl-N-(3-nitrophenyl)propane-2-sulfinamide; (R)-N-(3-Nitro-phenyl)-2-methyl-propane-2-sulfinamide; (R)-p-Toluenesulfinamide, N-(3-nitrophenyl)- (obsolete); (R)-3-Nitro-N-(tert-butylsulfinyl)aniline
EINECS	Contact for details

Quality Control

Our (R)-n-(3-Nitrophenyl) tert-Butanesulfinamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including chiral purity determination by HPLC. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.