Description

4-Methoxycarbonyl-2-Trifluoromethylphenylboronic Acid Pinacol Ester is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) containing the trifluoromethylphenyl moiety, which enhances metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aryl coupling reactions.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and semiconductors, where the boronic ester group facilitates polymerization or functionalization.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology & Probe Synthesis: Utilized to create molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-Methoxycarbonyl-2-Trifluoromethylphenylboronic Acid Pinacol Ester
CAS No.	1371589-09-1
Molecular Formula	C16H19BF3O4
Molecular Weight	343.13 g/mol
Synonyms	[4-(Methoxycarbonyl)-2-(trifluoromethyl)phenyl]boronic acid pinacol ester; 2-(Trifluoromethyl)-4-(methoxycarbonyl)benzeneboronic acid pinacol ester; 4-Carbomethoxy-2-trifluoromethylbenzeneboronic acid pinacol ester; Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)benzoate; Pinacol [4-(methoxycarbonyl)-2-(trifluoromethyl)phenyl]boronate; Boronic acid, B-[4-(methoxycarbonyl)-2-(trifluoromethyl)phenyl]-, 1,1-dimethylethyl ester (9CI)
EINECS	Contact for details

Quality Control

Our 4-Methoxycarbonyl-2-Trifluoromethylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to minimize exposure to atmospheric moisture. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.